Public Talk on Back Pain‏

Dear All

Something not to be missed!

In conjunction with the Chiropractic Workshop this coming weekend, IMU is organising a public talk (by Dr Phillip Ebrall) and demonstration of the analysis and correction of back problems (by Dr George Le Beau) for the public, on 1 November 2009 (Sunday) @ 1.30pm - 3.30pm at IMU Bukit Jalil Campus. Admission is free and all of you are invited to join.

Please inform your friends, relatives, neighbours too about this event and please call us to register as we only have limited places :-)

Thanks!

Infant colic poster

Dear batchmates, this is the poster from our group on INFANT COLIC.

Just in case you guys wanna know more bout it cos we don't have lecture on this topic.

Please click for a larger view and I think that you need to copy it then you zoom in to read the words.

Here is an important point which we missed:

Normally it goes off when the baby is 3 - 4 months old.

Happy studying and good luck and all the best.

*FIGHTING!*

:)

Halloween Night 2009

In 2007 IMU adopted Kampung Orang Asli Serendah as one of it's homes for it's Community and Social Responsibility Programme.

One of the challenges faced by the Orang Asli there is unclean water. Without proper water supply, the residents are vulnerable to many water-borne illnesses. The idea of raising funds is to be able to provide them with a manual water pump. Each pump (+ installation of the pump) costs about RM 2500, and we hope to raise enough money for at least one (or more) pump(s). This will enable the residents to have a supply of properly sanitized water and reduce the number of residents with water-borne illnesses.

And so in order to raise funds for the water pump(s), SRC Bukit Jalil will be hosting a Halloween Night celebration and you're invited!

Tickets can be purchased from any of the Vice-Presidents and are for only RM 12!

If you are planning to bring people outside of IMU you will need to provide us with their:

* Name
* IC/Passport Number
* Handphone number


For any other enquiries please e-mail imusrc@gmail.com.

We hope to see you there! :)

Acoustic Night

Date: 27th October

Time: 7pm onwards

Venue: Dance studio

Admission: Free (anyone)

Light refreshments will be provided.

Happy Deepavali everyone...

Hey.... Deepavali is here.. :) Wish our indian friends and everyone a Happy Deepavali..

Would be nice if each of us drops a wish here in the comment box... :)

Acne Talk by Prof. Ong Kok Hai

Date: October 16th 2009
Time: 12.45 PM to 1.30 PM
Venue: LT3

Participants will get free samples and there will be light refreshments. After the session students can have a one-on-one talk with Prof. Ong Kok Hai.

Did you know Prof. Ong Kok Hai has a product called Bio-Ti for acne treatment? For more info, read this article, or visit the company's site. [He also helped come up with TyphiDot which is a dot ELISA kit which detects IgM and IgG antibodies against S. Typh. Pretty cool, huh?]

Sex Education Talk‏

IMU will be having a talk on Sex Education on Monday, 26th October at 2.15pm in LT3.

Bibliography of speaker
Dr. Xavier V. Pereira
- MBBS(St.John's). MPsych Med (UM) ACIPT (Psychotherapy- Aus.) MISIPT
Dr Xavier is a consultant psychiatrist & psychotherapist, chair of the Malaysian & ASEAN Chapters of Interpersonal Psychotherapy (therapy for relationships), regular guest speaker for Big Bro Programme, Red 104.9fm in the year 2006 and conducts regular sessions for the community on various topics using psychological, social & spiritual approaches.

IMU Clothing Competition

Go to this address to vote!

http://its.imu.edu.my/imusurvey/index.php?sid=92346&newtest=Y&lang=en

MIC thingy- to be compiled =)

hi hi..i'm goin to compile all d MIC stuff in a CD..to b handed to mr farrukh. Currently what is lacking now are posters' soft copies. All respective groups pls email them to me k? =)
kyliew87@hotmail.com

Log Book Q5 & Q6

Hi. Here are some converstations in the interview and I think that they might be helpful in answering question 5 and 6.

Question 5:

"Q. Can you describe your company’s storage facility and storage conditions?
A. Poisons are kept in a cage under a lock system with the key held by the pharmacist. Other drugs are kept in normal designated areas. For raw materials and blister packaging materials such as aluminium foil, storage temperature is 23 ± 2°C with relative humidty of below 50%. Relative humidity is monitored daily with a hygrometer. Other packaging materials such as bottles can be stored at room temperature. "

Question 6:

"Q. Does Innovax utilize documents such as invoices, indents and GRN?
A. Most of their material is sourced from their subsidiaries thus they only need to purchase API’s from outside. Hence, invoices are only used for purchase of API’s. Invoices are managed by the administration. GRN is seldom used as it is more for the production side."

*What is GRN? (goods return note)

•GRN is being used to record all stocks or inventory returned to the suppliers especially damaged or wrongly delivered Goods
•Any damaged or wrongly delivered goods be received, the supplier should be notified immediately and agreement reached as to whether the stores are willing to receive a short order, the process necessary to get the damaged or wrongly delivered goods returned and arrange for the required items to be supplied.
•All messages or conversations with the supplier or his carrier regarding this matter should be noted on the relevant GRN as a record. On occasions any agreements reached may need to be put in writing and a copy of the letter filed appropriately.
•If further goods are expected the GRN should be placed in an incomplete order file to await further deliveries to complete the order.

Pharmaceutics Log Book Questions 1 and 2

1 . Describe the interrelation between preformulation and formulation process.

( Refer to aulton page 137)
- Preformulation stages are denoted as dotted boxes while formulation stages are solid boxes.
- In order to develop three of these dosage forms, tablets, capsules and injections, it is necessary to have the fundamental physical and chemical properties of the drug molecule and other derived properties of the drug powder are obtained.
- This information is essential to dictate many of the forthcoming events and approaches in formulation development.


2. Enumerate the importance of salt formation and crystallization of active pharmaceutical ingredients in pre-formulation studies.

- Major improvement in solubility can be achieved by salt formation.
- Preferably salts should be prepared from weak acid or base to prevent instability in tablet or capsule formation as more hygroscopic drugs tend to dissolved in its own adsorbed films of moisture.
- Less soluble salts tend to be less hygroscopic and form less acidic or basic solution which is useful in injection formulation.
- The pH of injection should be in between 3-9 to prevent vessel or tissue damage and pain at injection site. Furthermore, oral syrups should not be too acidic to make it more palatability.

- A weak base tends to be freely soluble in the gastrointestinal tract with no absorption seen as the drug is in ionized forms and absorption delayed until the intestine and vice versa for weak acid.
- Unlike weak base or acid, formation of salt allows better control of the pH of diffusion layer.
- This is an advantage as the diffusion layer acts as a buffering agent that adjusts the pH of the drug according to its environment in. Thus maximize the dissolution rate. Plus the dissolution rate of salt is usually greater than parent drug.

Log book ans for Q 11 (Updated with Q12)

The question is very difficult to answer. For Q11 u can refer to mr tham's presentation. It is available in I drive under Dr Rajinikhan folder. The next question still in progress....

Ok. Update..
This is another case of failed pharmaceutical marketing:

Exubera (inhaled insulin by Pfizer, introduced at mid-2006 but pulled out of market during 2007)

http://money.cnn.com/2007/10/19/magazines/fortune/simons_pfizer_erbitux.fortune/index.htm?postversion=2007101916

http://www.businessweek.com/magazine/content/06_29/b3993052.htm

http://www.worldofdtcmarketing.com/files/14c9d6ed0f21b0416916583dbcf79edf-166.html

http://www.drugs.com/pro/exubera.html

Updated

q12 Paracetamol:

http://www.superbrands-brands.com/volII/brand_panadol.htm

Here you can find some info about panadol and how they market panadol. For example, introduce diff dosage from and so on...

Here is another link for panadol....

http://www.filefreak.com/files/73880_hk6j8/panadol.pdf

Log Book: Vaccines

Here are the answers for the vaccines' part.

7. Explain the various QC tests for vaccines?

8. Explain the various stages involved in manufacturing of vaccines?
Surveillance where the wild virus are collected-->dominant strains are selected to prepare the seed virus--> The selected seed virus are passaged into eggs and working seed is developed--> bulk manufacturing process and production which includes fertilization, inoculation, incubation, candling, harvesting, clarification, purification, inactivation and sterile filtration--> purification and testing --> Formulation, filling and packaging

# If any of u need further explanation, u have to wait for the presentation on Monday =p

Proud to be part of B107

Suddenly i become emo..

Just wanna say, I am proud to be part of B107..

So so grateful to see a united B107... We stand as one, no matter what skin colour we have.. This is what we call 1Malaysia.. :)

Thanks Yen Nee for the template.. :P You are great...

Organ Donation Talk‏

Dear All,

Speaker : Mr Lee Chen Hoe
Topic : Organ donation
Venue : IMU LT3
Time : Friday 9 October 2009. 10:30AM to 11:15AM

There will be organ donation forms for those who wish to pledge to be donors.

Mr Lee was on dialysis for 5 years before getting a kidney transplant on 27 July 1996. The kidney was donated by the family of an American who was working in KL and died of a stroke. Mr Lee is the secretary of the Green Ribbon Support Association, which is a support group for organ transplant recipients. He is extremely active in the community by giving talks on organ donation.

Some Possible objections to donation organ are

1. doctors won't save me if I am in a medical emergency they know I am a donor
2. my religion is against organ donation
3. organs donated go to rich patients
4. I may not be dead before my organs are removed for transplant.

Are there any basis to these -- and many other -- objections ?

Please attend the talk.

Logbook ques. 9 & 10

This is from group 6

9.What is the importance of Batch Manufacturing Record (BMR) in injectables production and Quality Control (QC)?

Ans: Traceability in case of any error or problems.

10. List any one evaluation method of injectables you have observed

Ans: Pls refer notes from last sem. Eg: LAL test, clarity test, etc.

Ans from Pharmacist interviewed.

Logbook Ques. 3&4

Hey, hereby come with the points for Question 3 & 4 from my group (Group 2).

Question 3:
The basic considerations:
- Mixing devices, like homogenizers, high-speed stirrer, for oil and waer phases of emulsion
- Packaging of IV emulasion in the infusion bottles: purging of nitrogen gas into the bottles while capping
- Sterility maintenance: use of autoclave sterilization
- Particle size uniformity because presence of droplet size > 5 micrometers leads to embolism in the blood vessels.


Question 4:

•The weight sheet:
- clearly identifies the chemicals required in a batch.
- presents the chemicals in the quantities and the order in which they will be used
- prevents confusion the names and identifying numbers for the ingredients should be used on batch records.

•Precise and explicir process directions are given.
•Batch record provides:
1.Processing details
2.Sampling directions
3. In-process specifications
4. Finished product specifications
5. Countersignatures

•Various specifications like addition rates, mixing time, mixing speed, heating, and cooling rates, temperature, storing of the finished product samples are mentioned in the batch record directions.
•A manufacturing procedure is written by the actual operator with current knowledge and experience.

P/S: Answers asked from group supervisor =P

The LOG BOOK

Hello everyone...

As for the logbook...the part where there are 12 questions....
Actually, there are 2 questions from each topic. So, there are 6 groups, 6 topics and 12 questions.
So, it will be good if the answer for the questions in the logbook are given during the respective presentations and/or the posters...
We help each and other as there is time restriction for everyone!!!

More People Needed

IMU need more of Bpharm student to join the intervarsity event I mentioned in the earlier post in Nottingham University. Please check the previous posts for more info.

So far got a few from our batch going, so I thought it would be much funner if more can make it. So contact me ok if interested. Bus will be provided.

Poster for MIC

Hey everyone...

Regarding the poster for MIC, I can help to print it for u if u want.
It is of good quality with matte lamination.
As for the price, it depends on the poster (colour/s).

However, u need to email me the poster (in pdf or jpeg format) by this friday, 10am (latest). Please don't be late.
I'll pass u all the posters on Monday morning or come and get it from me on Sunday nite.
My email is anjali_rama@yahoo.com

Regards,
Anitha

Itinerary a.k.a Timetable

This is an update regarding the event in Nottingham that I posted not long ago. For those who are interested to know what they have in store, here is the timetable:

Itinerary (Draft)
9.30 Arrival of Guests/Pharmacy students from Universities
10.10 Welcoming speech by Professor Doughty (Dean of Pharmacy School)
12.30 Ice Breaking Session
-item games
-photo hunt
12.30 Lunch
13.30 A talk by pharmaceutical company (GSK)
-topic to be decided and confirmed by GSK
14.30 Raising awareness about A(H1N1) in Malaysia (competition)
16.30 Prize-giving and Farewell
18.00 END (Tentative time)